DUX4, Mouse, ATTO390, Clone: P2B1, Abnova™

Catalog No.	Quantity
89-109-592	100 μg

Catalog No. 89-109-592 Supplier Abnova Corporation Supplier No. MAB11443

Description

Mouse monoclonal antibody raised against recombinant partial DUX4.

This gene is located within a D4Z4 repeat array in the subtelomeric region of chromosome 4q. The D4Z4 repeat is polymorphic in length; a similar D4Z4 repeat array has been identified on chromosome 10. Each D4Z4 repeat unit has an open reading frame (named DUX4) that contains two homeoboxes; the repeat-array and ORF is conserved in other mammals. There was no evidence for transcription from standard cDNA libraries however RTPCR and in-vitro expression experiments indicate that the ORF is transcribed and the encoded protein has been reported to function as a transcriptional activator of paired-like homeodomain transcription factor 1 (PITX1; GeneID 5307). Contraction of the microsatellite repeat causes autosomal dominant facioscapulohumeral muscular dystrophy (FSHD). [provided by RefSeq

Specifications

• Antigen: DUX4
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot
• Classification: Monoclonal
• Clone: P2B1
• Conjugate: Atto 390
• Description: Mouse monoclonal antibody raised against recombinant partial DUX4.
• Dilution: Western Blot (1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.4 (50% glycerol, 0.09% sodium azide)
• Gene: DUX4
• Gene Alias: DUX10
• Gene Symbols: DUX4
• Host Species: Mouse
• Immunogen: Recombinant GST fusion protein corresponding to a 76 amino acid fragment at C-terminus of human DUX4.
• Purification Method: Protein G purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 22947
• Test Specificity: This antibody recognizes human DUX4. It does not cross-react with DUX4c.
• Target Species: Human
• Content And Storage: Store at 4°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1