MilliporeSigma™ Mouse anti-Dysferlin/DYSF, Clone: 10H3.1,

Catalog No.	Quantity
MABC974MI	100 μg

Catalog No. MABC974MI Supplier MilliporeSigma™ Supplier No. MABC974

Description

Mouse Monoclonal Antibody

Specifically detects Dysferlin/DYSF clone: 10H3.1 in Human samples, and it is validated for Immunohistochemistry (Paraffin), Western Blotting

Dysferlin (UniProt O75923; also known as Dystrophy-associated fer-1-like 1 protein, Fer-1-like family member 1, Fer-1-like protein 1, Limb girdle muscular dystrophy 2B (autosomal recessive) is encoded by the DYSF (also known as FER1L1, LGMD2B, MMD1) gene (Gene ID 8291) in human. Dysferlin is a member of the ferlin family of calcium-dependent phospholipid-binding proteins involved in membrane vesicle fusion, membrane repair, T-tubule stability, and calcium homeostasis. Defects in dysferlin function/expression leads to muscular dystrophies (dysferlinopathies) that include Miyoshi myopathy (MM), limb-girdle muscular dystrophy type 2B (LGMD-2B), and distal myopathy with anterior tibial onset (DMAT).

Specifications

• Antigen: Dysferlin/DYSF
• Applications: Immunohistochemistry (Paraffin), Western Blot
• Classification: Monoclonal
• Clone: 10H3.1
• Formulation: Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
• Gene Accession No.: O75923
• Gene Symbols: DYSF; FER1L1
• Host Species: Mouse
• Immunogen: GST-tagged recombinant protein corresponding to the N-terminal of human Dysferlin/DYSF.
• Purification Method: Protein G Purified
• Quantity: 100 μg
• Regulatory Status: RUO
• Research Discipline: Apoptosis, Cancer
• Primary or Secondary: Primary
• Gene ID (Entrez): NP_003485
• Target Species: Human
• Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
• Form: Purified
• Isotype: IgG2b κ

For Research Use Only