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Description
This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia. [provided by RefSeq
Specifications
Specifications
| Antigen | EDAR |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 3A7 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a partial recombinant EDAR. |
| Formulation | ascites with no preservative |
| Gene | EDAR |
| Gene Accession No. | NM_022336 |
| Gene Alias | DL/ED1R/ED3/ED5/EDA-A1R/EDA1R/EDA3/FLJ94390 |
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