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Description
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq
Specifications
Specifications
| Antigen | EGFR |
| Applications | Flow Cytometry, Immunoprecipitation, Western Blot |
| Classification | Monoclonal |
| Clone | EM-13 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against synthetic peptide of EGFR. |
| Dilution | Flow Cytometry Immunoprecipitation Western Blot (1 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS, pH 7.4 (0.09% sodium azide) |
| Gene | EGFR |
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