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EIF4E, Mouse, Clone: 5D11, Abnova™

Catalog No. 89108829 Shop All Abnova Corporation Products
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89-108-829 100 μL
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Catalog No. 89-108-829 Supplier Abnova Corporation Supplier No. MAB10633
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Description

Mouse monoclonal antibody raised against partial recombinant EIF4E.

All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide). This structure is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export. EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs. It is a 24kDa polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F. The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis. The other subunits of EIF4F are a 50kDa polypeptide, termed EIF4A (see MIM 601102), that possesses ATPase and RNA helicase activities, and a 220kDa polypeptide, EIF4G (MIM 600495) (Rychlik et al., 1987 [PubMed 3469651]).[supplied by OMIM

Specifications

Antigen EIF4E
Applications ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
Classification Monoclonal
Clone 5D11
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against partial recombinant EIF4E.
Dilution ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) Immunofluorescence (1:200-1:1000) Flow cytometry (1:200-1:400) The optimal working dilution should be determined by the end user.
Formulation In ascites (0.03% sodium azide)
Gene EIF4E
Gene Alias CBP/EIF4E1/EIF4EL1/EIF4F/MGC111573
Gene Symbols EIF4E
Host Species Mouse
Immunogen Recombinant protein corresponding to human EIF4E.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1977
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1
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