ENG, Mouse, Clone: MEM-226, Abnova™

Catalog No.	Quantity
89-111-633	100 μg

Catalog No. 89-111-633 Supplier Abnova Corporation Supplier No. MAB3850

Description

Mouse monoclonal antibody raised against recombinant ENG.

This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq

Specifications

• Antigen: ENG
• Applications: Flow Cytometry, Immunoprecipitation, Western Blot
• Classification: Monoclonal
• Clone: MEM-226
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against recombinant ENG.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.4 (0.09% sodium azide)
• Gene: ENG
• Gene Alias: CD105/END/FLJ41744/HHT1/ORW/ORW1
• Gene Symbols: ENG
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to human ENG.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2022
• Test Specificity: This antibody reacts with CD105 (Endoglin), a 180 KDa type I homodimerizing membrane glycoprotein expressed on vascular endothelial cells (small and large vessels), activated monocytes and tissue macrophages, stromal cells of certain tissues including bone marrow, pre-B lymphocytes in fetal marrow and erythroid precursors in fetal and adult bone marrow; it is also present on syncytiotrophoblast on placenta throughout pregnancy.
• Target Species: Human
• Content And Storage: Store at 4°C. Do not freeze.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG2a