EP300, Mouse, Clone: RW105, Abnova™

Mouse monoclonal antibody raised against partial recombinant EP300.

Supplier:  Abnova Corporation MAB2385

Catalog No. 89-110-980

Description

This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq

Specifications

• Antigen: EP300
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Western Blot (1:250-1:500) The optimal working dilution should be determined by the end user.
• Gene: EP300
• Gene Symbols: EP300
• Immunogen: Recombinant protein corresponding to amino acids 1572-2371 of human EP300.
• Regulatory Status: RUO
• Gene ID (Entrez): 2033
• Target Species: Human, Mouse, Primate, Rat
• Form: Liquid

• Applications: Immunofluorescence, Immunoprecipitation, Western Blot
• Clone: RW105
• Description: Mouse monoclonal antibody raised against partial recombinant EP300.
• Formulation: In PBS, pH 7.4 (0.09% sodium azide)
• Gene Alias: KAT3B/p300
• Host Species: Mouse
• Quantity: 200 μL
• Primary or Secondary: Primary
• Test Specificity: This antibody is specific to p300 protein. This antibody recognizes residues 1921-2023.
• Content And Storage: Store at -20°C or -80°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1 κ