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EP300, Mouse, Clone: RW128, Abnova™
Mouse monoclonal antibody raised against partial recombinant EP300.
Supplier: Abnova Corporation MAB2384
Description
This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq
Specifications
EP300 | |
Monoclonal | |
Unconjugated | |
Western Blot (1:250-1:500) The optimal working dilution should be determined by the end user. | |
EP300 | |
EP300 | |
Recombinant protein corresponding to amino acids 1572-2371 of human EP300. | |
RUO | |
2033 | |
Human, Mouse, Primate, Rat | |
Liquid |
Immunofluorescence, Immunoprecipitation, Western Blot | |
RW128 | |
Mouse monoclonal antibody raised against partial recombinant EP300. | |
In PBS, pH 7.4 (0.09% sodium azide) | |
KAT3B/p300 | |
Mouse | |
200 μL | |
Primary | |
This antibody is specific to p300 protein. This antibody recognizes residues 1868-1921. | |
Store at -20°C or -80°C. Aliquot to avoid repeated freezing and thawing. |
|
IgG1 κ |
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