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EP300, Mouse, Clone: RW128, Abnova™

Mouse monoclonal antibody raised against partial recombinant EP300.

Supplier:  Abnova Corporation MAB2384

Catalog No. 89-110-979


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Description

Description

This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq

Specifications

Specifications

EP300
Monoclonal
Unconjugated
Western Blot (1:250-1:500) The optimal working dilution should be determined by the end user.
EP300
EP300
Recombinant protein corresponding to amino acids 1572-2371 of human EP300.
RUO
2033
Human, Mouse, Primate, Rat
Liquid
Immunofluorescence, Immunoprecipitation, Western Blot
RW128
Mouse monoclonal antibody raised against partial recombinant EP300.
In PBS, pH 7.4 (0.09% sodium azide)
KAT3B/p300
Mouse
200 μL
Primary
This antibody is specific to p300 protein. This antibody recognizes residues 1868-1921.
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.
IgG1 κ
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