Mouse anti-ErbB2/Her2, Clone: HRB2/718, Azide Free, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP2346430.2 MG

Catalog No. NBP23464302

Description

ErbB2/Her2 Monoclonal antibody specifically detects ErbB2/Her2 in Human samples. It is validated for Flow Cytometry, ELISA, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Frozen, CyTOF-ready.

Specifications

• Antigen: ErbB2/Her2
• Clone: HRB2/718
• Conjugate: Unconjugated
• Formulation: 10mM PBS - BSA free with No Preservative
• Format: Purified
• Gene Symbols: ERBB2
• Immunogen: Recombinant extracellular domain of human HER-2 protein
• Molecular Weight of Antigen: 185 kDa
• Quantity: 0.2 mg
• Research Discipline: Breast Cancer, Cancer, Cellular Markers, Core ESC Like Genes, Phospho Specific, Protein Kinase, Stem Cell Markers, Tumor Suppressors
• Primary or Secondary: Primary
• Gene ID (Entrez): 2064
• Reconstitution: Protein A purified

• Applications: Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Frozen)
• Concentration: 1.0 mg/mL
• Dilution: Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 0.5-1ug/ml, Immunoprecipitation 0.5-1ug/500ug protein lysate, Immunohistochemistry-Frozen 0.5-1ug/ml, CyTOF-ready
• Gene Accession No.: P04626
• Gene Alias: CD340, CD340 antigen, c-erb B2/neu protein, EC 2.7.10, EGFR2, HER-2, HER2EC 2.7.10.1, herstatin, Metastatic lymph node gene 19 protein, MLN 19, MLN19, NEUHER-2/neu, neuroblastoma/glioblastoma derived oncogene homolog, NGLTKR1, p185erbB2, Proto-oncogene c-ErbB-2, Proto-oncogene Neu, receptor tyrosine-protein kinase erbB-2, Tyrosine kinase-type cell surface receptor HER2, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2(neuro/glioblastoma derived oncogene homolog), v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastomaderived oncogene homolog (avian)
• Host Species: Mouse
• Isotype: IgG1 Kappa
• Purification Method: Protein A purified
• Regulatory Status: RUO
• Storage Requirements: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Monoclonal or Polyclonal: Monoclonal
• Test Specificity: Recognizes a protein of 185kDa, which is identified as c-erbB-2/HER-2/neu. Its epitope is localized in the extracellular domain. C-erbB-2/HER-2 is a member of the EGFR family. This MAb is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.
• Target Species: Human

For Research Use Only