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Description
The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6)
Specifications
Specifications
| Antigen | ERCC4 |
| Applications | Immunohistochemistry, Western Blot |
| Classification | Monoclonal |
| Clone | 219 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against recombinant ERCC4. |
| Dilution | Western Blot (1-2 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) ( 2-4 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In 10mM PBS, pH 7.4 (0.09% sodium azide) |
| Gene | ERCC4 |
| Gene Alias | RAD1/XPF |
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