ESR1, Mouse, Clone: 2B7, Abnova™

Mouse monoclonal antibody raised against recombinant ESR1.

Supplier:  Abnova Corporation MAB10439

Catalog No. 89-108-625

Description

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq]

Specifications

• Antigen: ESR1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) ELISA (1:10000) The optimal working dilution should be determined by the end user.
• Gene: ESR1
• Gene Symbols: ESR1
• Immunogen: Recombinant protein corresponding to human ESR1.
• Regulatory Status: RUO
• Gene ID (Entrez): 2099
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1

• Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
• Clone: 2B7
• Description: Mouse monoclonal antibody raised against recombinant ESR1.
• Formulation: In PBS (0.03% sodium azide)
• Gene Alias: DKFZp686N23123/ER/ESR/ESRA/Era/NR3A1
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid