ESR1, Mouse, Clone: ER503, Abnova™

Catalog No.	Quantity
89-109-483	100 μg

Catalog No. 89-109-483 Supplier Abnova Corporation Supplier No. MAB11319

Description

Mouse monoclonal antibody raised against ESR1.

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. [provided by RefSeq]

Specifications

• Antigen: ESR1
• Applications: Flow Cytometry, Western Blot
• Classification: Monoclonal
• Clone: ER503
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against ESR1.
• Dilution: Flow Cytometry (0.5-1.0ug/10⁶ cells) Western Blot (0.5-1.0ug/ml for 2 hours at Room Temp) The optimal working dilution should be determined by the end user.
• Formulation: In 10mM PBS, pH 7.4 (0.05% BSA and 0.05% sodium azide)
• Gene: ESR1
• Gene Alias: DKFZp686N23123/ER/ESR/ESRA/Era/NR3A1
• Gene Symbols: ESR1
• Host Species: Mouse
• Immunogen: Recombinant human Estrogen Receptor alpha protein (amino acidss 2-185).
• Purification Method: Protein G purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2099
• Target Species: Human
• Content And Storage: Store at 4°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1 κ