ESR2, Mouse, Clone: ERb455, Abnova™

Catalog No.	Quantity
89-109-412	100 μg

Catalog No. 89-109-412 Supplier Abnova Corporation Supplier No. MAB11240

Description

Mouse monoclonal antibody raised against ESR2.

This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq

Specifications

• Antigen: ESR2
• Applications: Immunohistochemistry (PFA fixed)
• Classification: Monoclonal
• Clone: ERb455
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against ESR2.
• Dilution: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200-1:400) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.05% BSA, 0.05% sodium azide)
• Gene: ESR2
• Gene Alias: ER-BETA/ESR-BETA/ESRB/ESTRB/Erb/NR3A2
• Gene Symbols: ESR2
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to human ESR2.
• Purification Method: Protein G affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2100
• Target Species: Human
• Content And Storage: Store at 4°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1