F10, Mouse, Clone: F10-1, Abnova™

Catalog No.	Quantity
89-112-842	500 μg

Catalog No. 89-112-842 Supplier Abnova Corporation Supplier No. MAB6382

Description

Mouse monoclonal antibody raised against F10.

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. [provided by RefSeq]

Specifications

• Antigen: F10
• Applications: ELISA
• Classification: Monoclonal
• Clone: F10-1
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against F10.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: Lyophilized from 10mM PBS, pH 7.2
• Gene: F10
• Gene Alias: FX/FXA
• Gene Symbols: F10
• Host Species: Mouse
• Immunogen: Human F10.
• Quantity: 500 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2159
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot after reconstitution to avoid repeated freezing and thawing.
• Form: Lyophilized
• Isotype: IgG1 κ