F11, Mouse, Monoclonal Antibody, Abnova™

Mouse monoclonal antibody raised against native F11.

Supplier:  Abnova Corporation MAB0272

Catalog No. 89-107-900

Description

This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. [provided by RefSeq

Specifications

• Antigen: F11
• Classification: Monoclonal
• Description: Mouse monoclonal antibody raised against native F11.
• Formulation: In PBS (50% glycerol)
• Gene Alias: FXI/MGC141891
• Host Species: Mouse
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: This antibody recognizes human factor XI, 125I-factor XI, human factor XIa, BEGRck-factor XIa. It will inhibits clotting.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG

• Applications: ELISA, Radioimmune Assays (RIA), Western Blot
• Conjugate: Unconjugated
• Dilution: Western Blot (5 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: F11
• Gene Symbols: F11
• Immunogen: Native purified Human F11.
• Regulatory Status: RUO
• Gene ID (Entrez): 2160
• Target Species: Human
• Form: Liquid