F7, Mouse, Monoclonal Antibody, Abnova™

Catalog No.	Quantity
89-107-897	100 μg

Catalog No. 89-107-897 Supplier Abnova Corporation Supplier No. MAB0263

Description

Mouse monoclonal antibody raised against native F7.

This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Alternative splicing of this gene results in 2 transcripts. Defects in this gene can cause coagulopathy. [provided by RefSeq

Specifications

• Antigen: F7
• Applications: ELISA, Radioimmune Assays (RIA), Western Blot
• Classification: Monoclonal
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against native F7.
• Dilution: Western Blot (5 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (50% glycerol)
• Gene: F7
• Gene Symbols: F7
• Host Species: Mouse
• Immunogen: Native purified Human F7.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2155
• Test Specificity: This antibody recognizes human factor VII, factor VIIa, BFPRck factor VIIa.
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1