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F7, Mouse, Monoclonal Antibody, Abnova™

Mouse monoclonal antibody raised against native F7.

Manufacturer:  Abnova Corporation MAB0263

Catalog No. 89-107-897


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Description

Description

This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Alternative splicing of this gene results in 2 transcripts. Defects in this gene can cause coagulopathy. [provided by RefSeq

Specifications

Specifications

F7
Unconjugated
Western Blot (5 ug/mL) The optimal working dilution should be determined by the end user.
F7
F7
Native purified Human F7.
100 ug
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Monoclonal
This antibody recognizes human factor VII, factor VIIa, BFPRck factor VIIa.
ELISA, Radioimmune Assays, Western Blot
Mouse monoclonal antibody raised against native F7.
In PBS (50% glycerol)
Liquid
Mouse
IgG1
RUO
Primary
2155
Human
SDS
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