F8 Mouse anti-Human, Monoclonal Antibody, Abnova™

Catalog No.	Quantity
89-110-871	100 μg

Catalog No. 89-110-871 Supplier Abnova Corporation Supplier No. MAB2175

Description

Mouse monoclonal antibody raised against native F8.

This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq]

Specifications

• Antigen: F8
• Applications: ELISA
• Classification: Monoclonal
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against native F8.
• Dilution: ELISA (1:16000) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.4
• Gene: F8
• Gene Alias: AHF/DXS1253E/F8B/F8C/FVIII/HEMA
• Gene Symbols: F8
• Host Species: Mouse
• Immunogen: Native purified human F8.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2157
• Test Specificity: Recognize full-length human Factor VIII.
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1