FBLN5, Mouse, Clone: 1G6A4, Abnova™

Catalog No.	Quantity
89-108-751	100 μL

Catalog No. 89-108-751 Supplier Abnova Corporation Supplier No. MAB10560

Description

Mouse monoclonal antibody raised against partial recombinant FBLN5.

The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3). [provided by RefSeq

Specifications

• Antigen: FBLN5
• Applications: ELISA, Immunohistochemistry, Western Blot
• Classification: Monoclonal
• Clone: 1G6A4
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against partial recombinant FBLN5.
• Dilution: ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In ascites (0.03% sodium azide)
• Gene: FBLN5
• Gene Alias: ARMD3/DANCE/EVEC/FIBL-5/FLJ90059/UP50
• Gene Symbols: FBLN5
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to amino acids 242-448 of human FBLN5.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 10516
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1