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Description
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
Specifications
Specifications
| Antigen | FCAR |
| Applications | Western Blot |
| Classification | Monoclonal |
| Clone | MIP68b |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against partial recombinant FCAR. |
| Dilution | Western Blot (5 ug/mL) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS (0.09% sodium azide) |
| Gene | FCAR |
| Gene Alias | CD89 |
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