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FLG, Mouse, Clone: FLG01, Abnova™

Catalog No. 89111461 Shop All Abnova Corporation Products
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89-111-461 1 mL
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Catalog No. 89-111-461 Supplier Abnova Corporation Supplier No. MAB3538

Description

Mouse monoclonal antibody raised against recombinant FLG.

Profilaggrin is a major protein component of the keratohyalin granules of mammalian epidermis. It is initially expressed as a large polyprotein precursor which is subsequently proteolytically processed into individual functional filaggrin molecules. The filaggrins show wide species variations and their aberrant expression has been implicated in a number of keratinizing disorders (Baden et al., 1974 [PubMed 4132224]; Holbrook et al., 1982 [PubMed 6174530]; Sybert et al., 1985 [PubMed 2579164]).[supplied by OMIM

Specifications

Antigen FLG
Applications Immunohistochemistry
Classification Monoclonal
Clone FLG01
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against recombinant FLG.
Dilution The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.3 (BSA, 0.09% sodium azide)
Gene FLG
Gene Alias ATOD2
Gene Symbols FLG
Host Species Mouse
Immunogen Recombinant protein corresponding to human FLG.
Quantity 1 mL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2312
Test Specificity This antibody reacts with human filaggrin 38 KDa and pro-filaggrin (∼ 400 KDa).
Target Species Human
Content And Storage Store at 4°C. Do not freeze.
Form Liquid
Isotype IgG1 κ
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