FLG, Mouse, Clone: FLG01, Abnova™

Mouse monoclonal antibody raised against recombinant FLG.

Supplier:  Abnova Corporation MAB3538

Catalog No. 89-111-461

Description

Profilaggrin is a major protein component of the keratohyalin granules of mammalian epidermis. It is initially expressed as a large polyprotein precursor which is subsequently proteolytically processed into individual functional filaggrin molecules. The filaggrins show wide species variations and their aberrant expression has been implicated in a number of keratinizing disorders (Baden et al., 1974 [PubMed 4132224]; Holbrook et al., 1982 [PubMed 6174530]; Sybert et al., 1985 [PubMed 2579164]).[supplied by OMIM

Specifications

• Antigen: FLG
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: The optimal working dilution should be determined by the end user.
• Gene: FLG
• Gene Symbols: FLG
• Immunogen: Recombinant protein corresponding to human FLG.
• Regulatory Status: RUO
• Gene ID (Entrez): 2312
• Target Species: Human
• Form: Liquid

• Applications: Immunohistochemistry
• Clone: FLG01
• Description: Mouse monoclonal antibody raised against recombinant FLG.
• Formulation: In PBS, pH 7.3 (BSA, 0.09% sodium azide)
• Gene Alias: ATOD2
• Host Species: Mouse
• Quantity: 1 mL
• Primary or Secondary: Primary
• Test Specificity: This antibody reacts with human filaggrin 38 KDa and pro-filaggrin (∼ 400 KDa).
• Content And Storage: Store at 4°C. Do not freeze.
• Isotype: IgG1 κ