FOLH1, Mouse, Clone: 4H11, Abnova™

Catalog No.	Quantity
89-113-357	500 μg

Catalog No. 89-113-357 Supplier Abnova Corporation Supplier No. MAB8110

Description

Mouse monoclonal antibody raised against synthetic peptide of FOLH1.

This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq

Specifications

• Antigen: FOLH1
• Applications: ELISA, Immunohistochemistry
• Classification: Monoclonal
• Clone: 4H11
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against synthetic peptide of FOLH1.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: Lyophilized from 10mM PBS
• Gene: FOLH1
• Gene Alias: FGCP/FOLH/GCP2/GCPII/NAALAD1/NAALAdase/PSM/PSMA/mGCP
• Gene Symbols: FOLH1
• Host Species: Mouse
• Immunogen: A synthetic peptide corresponding to human FOLH1.
• Quantity: 500 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2346
• Target Species: Human
• Content And Storage: Store at -20°C.
  Aliquot after reconstitution to avoid repeated freezing and thawing.
• Form: Lyophilized
• Isotype: IgG1