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FTS, Mouse, Clone: 2B2, Abnova™

Catalog No. 89107281 Shop All Abnova Corporation Products
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89-107-281 200 μL
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Catalog No. 89-107-281 Supplier Abnova Corporation Supplier No. H00064400M01A
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Description

Mouse monoclonal antibody raised against a full-length recombinant FTS.

The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq]

Sequence: MNPFWSMSTSSVRKRSEGEEKTLTGDVKTSPPRTAPKKQLPSIPKNALPITKPTSPAPAAQSTNGTHASYGPFYLEYSLLAEFTLVVKQKLPGVYVQPSYRSALMWFGVIFIRHGLYQDGVFKFTVYIPDNYPDGDCPRLVFDIPVFHPLVDPTSGELDVKRAFAKWRRNHNHIWQVLMYARRVFYKIDTASPLNPEAAVLYEKDIQLFKSKVVDSVKVCTARLFDQPKIEDPYAISFSPWNPSVHDEAREKMLTQKKPEEQHNKSVHVAGLSWVKPGSVQPFSKEEKTVAT

Specifications

Antigen FTS
Applications ELISA, Western Blot
Classification Monoclonal
Clone 2B2
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against a full-length recombinant FTS.
Formulation ascites with no preservative
Gene AKTIP
Gene Accession No. BC001134
Gene Alias FT1/FTS
Gene Symbols AKTIP
Host Species Mouse
Immunogen FTS (AAH01134,1 a.a. ∽ 292 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Quantity 200 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64400
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Product Type Antibody
Form Ascites
Isotype IgG2a κ
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