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GCG, Mouse, Clone: IMD-7, Abnova™

Catalog No. 89110460 Shop All Abnova Corporation Products
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89-110-460 100 μg
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Catalog No. 89-110-460 Supplier Abnova Corporation Supplier No. MAB1500
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Mouse monoclonal antibody raised against native GCG.

The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq

Specifications

Antigen GCG
Applications Immunohistochemistry (PFA fixed)
Classification Monoclonal
Clone K79bB10
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against native GCG.
Dilution Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1-2 ug/mL) The optimal working dilution should be determined by the end user.
Formulation Lyophilized from 1.2% sodium acetate (2mg BSA, 0.01mg sodium azide)
Gene GCG
Gene Alias GLP1/GLP2/GRPP
Gene Symbols GCG
Host Species Mouse
Immunogen Native from porcine glucagon.
Purification Method Affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2641
Target Species Human, Rat
Content And Storage Store at -20°C on dry atmosphere. After reconstitution with 1mL of 1.2% sodium acetate or neutral PBS to a concentration of 100μg/mL store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Lyophilized
Isotype IgG1
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