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GFI1, Mouse, Polyclonal Antibody, Abnova™

Catalog No. 89104542 Shop All Abnova Corporation Products
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89-104-542 50 μL
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Catalog No. 89-104-542 Supplier Abnova Corporation Supplier No. H00002672A01
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Mouse polyclonal antibody raised against a partial recombinant GFI1.

This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene. [provided by RefSeq

Sequence: MPRSFLVKSKKAHSYHQPRSPGPDYSLRLENVPAPSRADSTSNAGGAKAEPRDRLSPESQLTEAPDRASASPRQLRSSVCERSSEFEDFWR

Specifications

Antigen GFI1
Applications ELISA, Western Blot
Classification Polyclonal
Conjugate Unconjugated
Description Mouse polyclonal antibody raised against a partial recombinant GFI1.
Formulation 50% glycerol
Gene GFI1
Gene Accession No. NM_005263
Gene Alias FLJ94509/GFI-1/ZNF163
Gene Symbols GFI1
Host Species Mouse
Immunogen GFI1 (NP_005254, 1 a.a. to 91 a.a) partial recombinant protein with GST tag.
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2672
Target Species Human
Content And Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Form Antisera
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For Research Use Only

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