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GNRHR, Mouse, Clone: F1G4, Abnova™

Catalog No. 89110691 Shop All Abnova Corporation Products
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89-110-691 100 μg
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Catalog No. 89-110-691 Supplier Abnova Corporation Supplier No. MAB1887

Description

Mouse monoclonal antibody raised against synthetic peptide of GNRHR.

This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. [provided by RefSeq]

Specifications

Antigen GNRHR
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
Classification Monoclonal
Clone F1G4
Conjugate Unconjugated
Description gonadotropin-releasing hormone receptor
Formulation In PBS (0.08% sodium azide)
Gene GNRHR
Gene Alias GNRHR1, GRHR, LHRHR, LRHR
Gene Symbols GNRHR
Host Species Mouse
Immunogen A synthetic peptide corresponding to amino acids 1-29 of human GNRHR.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2798
Content And Storage Store at -20°C. Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1
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