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Description
This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. [provided by RefSeq
Specifications
Specifications
| Antigen | GP9 |
| Applications | Flow Cytometry, Immunofluorescence |
| Classification | Monoclonal |
| Clone | GR-P |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against native GP9. |
| Dilution | Flow Cytometry (20 uL/106 cells) The optimal working dilution should be determined by the end user. |
| Formulation | In buffer containing 1% BSA, pH 7.2 (0.09% sodium azide) |
| Gene | GP9 |
| Gene Alias | CD42a/GPIX |
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