GPC3, Mouse, Clone: 1G12, Abnova™

Mouse monoclonal antibody raised against GPC3.

Supplier:  Abnova Corporation MAB10762

Catalog No. 89-108-963

Description

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq

Specifications

• Antigen: GPC3
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: The optimal working dilution should be determined by the end user.
• Gene: GPC3
• Gene Symbols: GPC3
• Immunogen: GPC3.
• Regulatory Status: RUO
• Gene ID (Entrez): 2719
• Form: Liquid

• Applications: Immunohistochemistry
• Clone: 1G12
• Description: Mouse monoclonal antibody raised against GPC3.
• Formulation: In PBS, pH 7.4 (protein base, 0.09% sodium azide)
• Gene Alias: DGSX/OCI-5/SDYS/SGB/SGBS/SGBS1
• Host Species: Mouse
• Quantity: 1 mL
• Primary or Secondary: Primary
• Content And Storage: Store at 4°C is stable for 3 years.
• Isotype: IgG1