GSK3B, Mouse, Clone: M131, Abnova™

Mouse monoclonal antibody raised against partial recombinant GSK3B.

Supplier:  Abnova Corporation MAB1372

Catalog No. 89-110-388

Description

The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene

Specifications

• Antigen: GSK3B
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:4000) Immunocytochemistry (1:1000) Western Blot (1:2000) The optimal working dilution should be determined by the end user.
• Gene: GSK3B
• Host Species: Mouse
• Quantity: 100 μL
• Primary or Secondary: Primary
• Test Specificity: This sequence is highly conserved in rat and mouse GSK-3b, but has low homology to GSK-3a.
• Form: Liquid

• Applications: ELISA, Western Blot
• Clone: M131
• Description: Mouse monoclonal antibody raised against partial recombinant GSK3B.
• Formulation: In PBS (50% glycerol, 1mg/mL BSA, 0.05% sodium azide)
• Gene Symbols: GSK3B
• Immunogen: Recombinant protein corresponding to N-terminus of human GSK3B.
• Regulatory Status: RUO
• Gene ID (Entrez): 2932
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG1