GSK3B, Mouse, Clone: M132, Abnova™

Catalog No.	Quantity
89-110-389	100 μL

Catalog No. 89-110-389 Supplier Abnova Corporation Supplier No. MAB1373

Description

Mouse monoclonal antibody raised against synthetic phosphopeptide of GSK3B.

The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene

Specifications

• Antigen: GSK3B
• Applications: ELISA, Western Blot
• Classification: Monoclonal
• Clone: M132
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against synthetic phosphopeptide of GSK3B.
• Dilution: ELISA (1:2000) Western Blot (1:500) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (50% glycerol, 1mg/mL BSA, 0.05% sodium azide)
• Gene: GSK3B
• Gene Symbols: GSK3B
• Host Species: Mouse
• Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y216 of human GSK3B.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 2932
• Test Specificity: This peptide sequence is also found in GSK-3a (Tyr-279) and is highly conserved in GSK-3 genes in rat and mouse.
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1