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Description
The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq
Specifications
Specifications
| Antigen | HAT1 |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against partial recombinant HAT1. |
| Dilution | Western Blot (1:100-1:2000) ELISA (1:5000-1:20000) The optimal working dilution should be determined by the end user. |
| Formulation | In PBS, pH 7.4 (0.02% sodium azide, 1% BSA, 50% glycerol) |
| Gene | HAT1 |
| Gene Accession No. | NM_003642.3 |
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