MilliporeSigma™ Mouse anti-HDAC1, Clone: 2E10,
Mouse Monoclonal Antibody
Supplier: MilliporeSigma™ 05100I
Specifically detects HDAC1 clone: 2E10 in Human, Mouse samples, and it is validated for Immunoprecipitation, Western BlottingHistone deacetylase 1 is a nuclear enzyme encoded by the Hdac1 gene (also known as HD1, RPD3, MommeD5, Hdac1-ps) in mouse and HDAC1 (also known as GoON-10, RPD3L1) gene in human. Hdac1 plays an important role in epigenetic regulation of gene expression by catalyzing the hydrolysis of N(6)-acetylated histone lysine residues. Hdac1 is also known to deacetylate p53 and thereby downregulate p53 activity.
|Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.|
|KLH-conjugated, synthetic peptide (C-EEKPEAKGVKEEVKLA) corresponding to amino acids 467-482 of mouse HDAC1. The immunizing sequence is identical in human.|
|Epigenetics and Nuclear Function|
|Stable for one year at 2°C to 8°C from date of receipt.|
|Immunoprecipitation, Western Blot|
|Protein G Purified|
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