MilliporeSigma™ Mouse anti-HDAC1, Clone: 2E10,

Mouse Monoclonal Antibody

Supplier:  MilliporeSigma™ 05100I

Catalog No. 05-100-IMI

Description

Specifically detects HDAC1 clone: 2E10 in Human, Mouse samples, and it is validated for Immunoprecipitation, Western Blotting

Histone deacetylase 1 is a nuclear enzyme encoded by the Hdac1 gene (also known as HD1, RPD3, MommeD5, Hdac1-ps) in mouse and HDAC1 (also known as GoON-10, RPD3L1) gene in human. Hdac1 plays an important role in epigenetic regulation of gene expression by catalyzing the hydrolysis of N(6)-acetylated histone lysine residues. Hdac1 is also known to deacetylate p53 and thereby downregulate p53 activity.

Specifications

• Antigen: HDAC1
• Classification: Monoclonal
• Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
• Gene Symbols: Hdac1
• Immunogen: KLH-conjugated, synthetic peptide (C-EEKPEAKGVKEEVKLA) corresponding to amino acids 467-482 of mouse HDAC1. The immunizing sequence is identical in human.
• Quantity: 100 μL
• Research Discipline: Epigenetics and Nuclear Function
• Gene ID (Entrez): NP_032254
• Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
• Isotype: IgG1 κ

• Applications: Immunoprecipitation, Western Blot
• Clone: 2E10
• Gene Accession No.: O09106
• Host Species: Mouse
• Purification Method: Protein G Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Form: Purified

For Research Use Only