HK1, Mouse, Clone: 3A10, Abnova™

Catalog No.	Quantity
89-108-883	100 μL

Catalog No. 89-108-883 Supplier Abnova Corporation Supplier No. MAB10683

Description

Mouse monoclonal antibody raised against partial recombinant HK1.

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein. [provided by RefSeq

Specifications

• Antigen: HK1
• Applications: ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Western Blot
• Classification: Monoclonal
• Clone: 3A10
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against partial recombinant HK1.
• Dilution: ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) Immunofluorescence (1:200-1:1000) Flow cytometry (1:200-1:400) The optimal working dilution should be determined by the end user.
• Formulation: In ascites (0.03% sodium azide)
• Gene: HK1
• Gene Alias: HK1-ta/HK1-tb/HK1-tc/HKI/HXK1
• Gene Symbols: HK1
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to human HK1.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3098
• Target Species: Human, Mouse, Rat
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1