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Description
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. [provided by RefSeq
Specifications
Specifications
| Antigen | HK2 |
| Applications | ELISA, Flow Cytometry, Immunohistochemistry, Western Blot |
| Classification | Monoclonal |
| Clone | 3D3 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against partial recombinant HK2. |
| Dilution | ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) Flow cytometry (1:200-1:400) The optimal working dilution should be determined by the end user. |
| Formulation | In ascites (0.03% sodium azide) |
| Gene | HK2 |
| Gene Alias | DKFZp686M1669/HKII/HXK2 |
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