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HLA-DMB, Mouse, Clone: 5G11, Abnova™
Mouse monoclonal antibody raised against a partial recombinant HLA-DMB.
Supplier: Abnova Corporation H00003109M06A
Description
HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. [provided by RefSeq
Sequence: VAHVESTCLLDDAGTPKDFTYCISFNKDLLTCWDPEENKMAPCEFGVLNSLANVLSQHLNQKDTLMQRLRNGLQNCATHTQPFWGSLTNRTRPPSVQVAKTTPFNTRESpecifications
HLA-DMB | |
Monoclonal | |
Unconjugated | |
ascites with no preservative | |
NM_002118 | |
HLA-DMB | |
HLA-DMB (NP_002109,22 a.a. ∽ 129 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
RUO | |
3109 | |
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
Ascites |
ELISA, Western Blot | |
5G11 | |
Mouse monoclonal antibody raised against a partial recombinant HLA-DMB. | |
HLA-DMB | |
D6S221E/RING7 | |
Mouse | |
200 μL | |
Primary | |
Human | |
Antibody | |
IgG2b κ |
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