HLA-DRA, Mouse, Clone: LN3, Abnova™

Catalog No.	Quantity
89-109-054	100 μg

Catalog No. 89-109-054 Supplier Abnova Corporation Supplier No. MAB10849

Description

Mouse monoclonal antibody raised against HLA-DRA.

HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq

Specifications

• Antigen: HLA-DRA
• Applications: Flow Cytometry, Immunohistochemistry
• Classification: Monoclonal
• Clone: LN3
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against HLA-DRA.
• Dilution: The optimal working dilution should be determined by the end user.
• Formulation: In aqueous buffer (0.09% sodium azide)
• Gene: HLA-DRA
• Gene Alias: HLA-DRA1
• Gene Symbols: HLA-DRA
• Host Species: Mouse
• Immunogen: Human HLA-DRA.
• Purification Method: Affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3122
• Test Specificity: The antibody reacts with HLA-DRA.
• Target Species: Human
• Content And Storage: Store at 4°C.
• Form: Liquid
• Isotype: IgG2b κ