HLA-DRA, Mouse, Clone: TAL 16.1, Abnova™

Mouse monoclonal antibody raised against HLA-DRA.

Supplier:  Abnova Corporation MAB7021

Catalog No. 89-113-115

Description

HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq

Specifications

• Antigen: HLA-DRA
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: The optimal working dilution should be determined by the end user.
• Gene: HLA-DRA
• Gene Symbols: HLA-DRA
• Immunogen: Human HLA-DRA.
• Regulatory Status: RUO
• Gene ID (Entrez): 3122
• Target Species: Human
• Form: Liquid

• Applications: ELISA, Flow Cytometry, Immunohistochemistry, Western Blot
• Clone: TAL 16.1
• Description: Mouse monoclonal antibody raised against HLA-DRA.
• Formulation: In PBS
• Gene Alias: HLA-DRA1
• Host Species: Mouse
• Quantity: 100 μg
• Primary or Secondary: Primary
• Test Specificity: HLA DR (TAL 16.1). Western Blot Predicted molecular weight 29 KDa.
• Content And Storage: Store at 4°C for short term. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Isotype: IgG2a