HLA-G, Mouse, PE, Clone: 87G, Abnova™

Catalog No.	Quantity
89-112-110	100 μg

Catalog No. 89-112-110 Supplier Abnova Corporation Supplier No. MAB5094

Description

Mouse monoclonal antibody raised against HLA-G.

HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq

Specifications

• Antigen: HLA-G
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: 87G
• Concentration: 0.1 mg/mL
• Conjugate: PE
• Description: Mouse monoclonal antibody raised against HLA-G.
• Dilution: Flow Cytometry (1:10) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.2% BSA, 0.09% sodium azide)
• Gene: HLA-G
• Gene Alias: MHC-G
• Gene Symbols: HLA-G
• Host Species: Mouse
• Immunogen: HLA-B27 transgenic mice were imunized with H-2 identical murine cells transfected with and expressing genes encoding HLA-G and human beta2-microglobulin.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3135
• Test Specificity: This antibody recognizes both membrane-bound and soluble forms of HLA-G (HLA-G1 and HLA-G5). This antibody blocks interaction of HLA-G with inhibitory receptors.
• Target Species: Human
• Content And Storage: Store in the dark at 4°C. Do not freeze.
  Avoid prolonged exposure to light.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG2a