HLA-G, Mouse, PE, Clone: MEM-G/9, Abnova™

Catalog No.	Quantity
89-112-088	100 μg

Catalog No. 89-112-088 Supplier Abnova Corporation Supplier No. MAB5059

Description

Mouse monoclonal antibody raised against recombinant HLA-G.

HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq

Specifications

• Antigen: HLA-G
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: MEM-G/9
• Concentration: 0.1 mg/mL
• Conjugate: PE
• Description: Mouse monoclonal antibody raised against recombinant HLA-G.
• Dilution: Flow Cytometry (1:100) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.2% BSA, 0.09% sodium azide)
• Gene: HLA-G
• Gene Alias: MHC-G
• Gene Symbols: HLA-G
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to human HLA-G refolded with beta2-microglobulin and peptide.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3135
• Test Specificity: This antibody reacts with native form of human HLA-G1 on the cell surface as well as with soluble HLA-G5 isoform in its beta2-microglobulin associated form. HLA-G belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on the surface of trophoblast cells.
• Target Species: Human
• Content And Storage: Store in the dark at 4°C. Do not freeze.
  Avoid prolonged exposure to light.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1