HP, Mouse, Clone: 1, Abnova™

Catalog No.	Quantity
89-113-853	100 μg

Catalog No. 89-113-853 Supplier Abnova Corporation Supplier No. MAB9895

Description

Mouse monoclonal antibody raised against partial recombinant HP.

This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Specifications

• Antigen: HP
• Applications: ELISA, Immunohistochemistry, Western Blot
• Classification: Monoclonal
• Clone: 1
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against partial recombinant HP.
• Dilution: Western blot (1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In Citrate-Tris-HCl buffer, pH 7.0 (0.02% Proclin 300)
• Gene: HP
• Gene Accession No.: NM_001126102
• Gene Alias: BP/HP2-ALPHA-2/HPA1S/MGC111141
• Gene Symbols: HP
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to amino acids 19-406 of human HP.
• Purification Method: Affinity purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3240
• Test Specificity: It can expression in BGC823 whole cell lysate.
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1