HRAS, Mouse, Clone: H-RAS-03, Abnova™

Catalog No.	Quantity
89-111-502	100 μg

Catalog No. 89-111-502 Supplier Abnova Corporation Supplier No. MAB3617

Description

Mouse monoclonal antibody raised against synthetic peptide of HRAS.

This gene belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. [provided by RefSeq

Sequence: DIHQYREQIKRVKDSDDC

Specifications

• Antigen: HRAS
• Applications: Western Blot
• Classification: Monoclonal
• Clone: H-RAS-03
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against synthetic peptide of HRAS.
• Dilution: Western Blot (0.5-1 ug/mL) The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.4 (0.09% sodium azide)
• Gene: HRAS
• Gene Alias: C-BAS/HAS/C-H-RAS/C-HA-RAS1/CTLO/H-RASIDX/HAMSV/HRAS1/K-RAS/N-RAS/RASH1
• Gene Symbols: HRAS
• Host Species: Mouse
• Immunogen: A synthetic peptide corresponding to human HRAS.
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3265
• Test Specificity: This antibody reacts with human HRAS, an ubiquitously expressed 21 KDa intracellular protein. Although reactivity with other species has not been determined, it is probable as the epitope is highly conserved among animals.
• Target Species: Human
• Content And Storage: Store at 4°C. Do not freeze.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1