HSPA5, Mouse, Clone: 4E3, Abnova™

Catalog No.	Quantity
89-108-889	100 μL

Catalog No. 89-108-889 Supplier Abnova Corporation Supplier No. MAB10689

Description

Mouse monoclonal antibody raised against partial recombinant HSPA5.

When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) [PubMed 8020977] pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell.[supplied by OMIM

Specifications

• Antigen: HSPA5
• Applications: ELISA, Immunohistochemistry, Western Blot
• Classification: Monoclonal
• Clone: 4E3
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against partial recombinant HSPA5.
• Dilution: ELISA (1:10000) Western Blot (1:500-1:2000) Immunohistochemistry (1:200-1:1000) The optimal working dilution should be determined by the end user.
• Formulation: In ascites (0.03% sodium azide)
• Gene: HSPA5
• Gene Alias: BIP/FLJ26106/GRP78/MIF2
• Gene Symbols: HSPA5
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to human HSPA5.
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3309
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1