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CD2 Mouse anti-Human, Brilliant Violet 786, Clone: RPA-2.10, BD Optibuild™

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 740960

Catalog No. BDB740960


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Description

Description

The RPA-2.10 monoclonal antibody specifically binds to CD2. CD2 is a 50 kDa single-chain transmembrane glycoprotein, also known as LFA-2 or the receptor for sheep erythrocytes. CD2 belongs to the immunoglobulin superfamily of proteins along with its ligand LFA-3, CD58. It is present on about 80-90% of human peripheral blood lymphocytes, greater than 95% of thymocytes, all T lymphocytes that form E-rosettes and a subset of NK cells. CD2 plays a role in T-cell signaling and in lymphocyte adhesion.

The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 786-nm. BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60-nm filter).

Specifications

Specifications

CD2
RPA-2.10
Brilliant Violet 786
Aqueous buffered solution containing ≤0.09% sodium azide.
Murine
IgG1, κ
50μg
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
Flow Cytometry
0.2mg/mL
LFA-2; Lymphocyte function antigen-2; T11/Leu-5; Rosette receptor
Affinity Purified
Human Phytohemagglutinin-treated Lymphoblasts
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
RUO
Primary
Human
Documents
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