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CD27 Mouse anti-Human, Brilliant Violet 510, Clone: M-T271, BD Optibuild™

Catalog No. BDB740167 Shop All BD Biosciences Products
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Catalog No. BDB740167 Supplier BD Biosciences Supplier No. 740167
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Mouse Monoclonal Antibody

The M-T271 monoclonal antibody specifically binds to CD27. CD27 presents as a type I transmembrane, disulphide-linked 110 kDa homodimer comprised of two polypeptide chains. The CD27 molecule is a lymphocyte-specific member of the TNF/NGF-R family, and is expressed on a subset of human thymocytes and on the majority of mature T lymphocytes, activated B cells and NK cells. CD27 is highly induced on T cells after TCR stimulation. CD27 binds to CD70 (also known as, CD27 ligand or CD27L) and may be involved in cellular interaction of T and B lymphocytes.

The antibody was conjugated to BD Horizon™ BV510 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 405-nm and Em Max at 510-nm, BD Horizon BV510 can be excited by the violet laser and detected in the BD Horizon V500 (525/50-nm) filter set. BD Horizon BV510 conjugates are useful for the detection of dim markers off the violet laser.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD27
Applications Flow Cytometry
Classification Monoclonal
Clone M-T271
Concentration 0.2mg/mL
Conjugate Brilliant Violet 510
Description TNFRSF7; TNF receptor superfamily, member 7; T14; Tp55; S152
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human T-CLL cells
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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