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CD63 Mouse anti-Human, Brilliant Violet 786, Clone: H5C6, BD Optibuild™
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The H5C6 monoclonal antibody specifically binds to CD63. CD63 is a 53 kDa, type III lysosomal glycoprotein, expressed on activated platelets, monocytes and macrophages. This molecule is also referred to in the literature as LIMP, gp55, melanoma-associated antigen ME491, Pltgp40, LAMP-3 and is a member of the tetraspan transmembrane 4 superfamily (TM4SF). It is widely expressed on surface and in the cytoplasm of various hematopoietic (monocytes, macrophages) and non-hematopoietic (endothelium, fibroblasts, osteoclasts, smooth muscle) cells. CD63 plays roles in mediating cellular adhesion and motility.
The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 786-nm. BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60-nm filter).
Specifications
Specifications
| Antigen | CD63 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | H5C6 |
| Concentration | 0.2mg/mL |
| Conjugate | Brilliant Violet 786 |
| Description | LAMP-3; ME491; MLA-1; Granulophysin; Ptgr40; NGA; gp55 |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide. |
| Host Species | Mouse |
| Immunogen | Human Splenic Adherent Cells |
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For Research Use Only
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