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CD64 Mouse anti-Human, Brilliant Violet 711, Clone: 10.1, BD Optibuild™

Catalog No. BDB740782 Shop All BD Biosciences Products
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BDB740782 50 μg
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Catalog No. BDB740782 Supplier BD Biosciences Supplier No. 740782
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Description

Mouse Monoclonal Antibody

The 10.1 monoclonal antibody specifically binds to CD64, a 72 kDa type I transmembrane glycoprotein that is a high affinity receptor for human IgG (FcγRI), especially the IgG1 and IgG3 subclasses. CD64 is expressed on monocytes, macrophages, dendritic cells, granulocytes activated with interferon-gamma and early myeloid lineage cells. CD64 associates with a signaling FcRγhomodimer to form the functional high affinity FcγRI complex. CD64 functions in both innate and adaptive immune responses and mediates endocytosis, phagocytosis, antigen presentation, antibody-dependent cellular toxicity, cytokine release and superoxide generation.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD64
Applications Flow Cytometry
Classification Monoclonal
Clone 10.1
Concentration 0.2mg/mL
Conjugate Brilliant Violet 711
Description FCGR1; FcRI; Fc-gamma RI; IgG Fc Receptor I; High affinity IgG FcR1
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human Rheumatoid synovial fluid cells and fibronectin-purified monocytes
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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