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CD66 Mouse anti-Human, Brilliant Violet 650, Clone: B1.1/CD66, BD Optibuild™
Mouse Monoclonal Antibody
Supplier: BD Biosciences 740607
Description
The B1.1 monoclonal antibody binds to several glycosylphosphatidylinositol-anchored glycoproteins present on granulocytes and epithelial cells. As reported in the Sixth International Workshop and Conference on Human Leucocyte Differentiation Antigens, the B1.1 antibody recognized CD66a ( CEACAM1 ), CD66c ( CEACAM6 ), CD66d ( CEACAM3 ) and CD66e ( . These molecules exhibit both homophilic and heterophilic adhesion. CEA family members may be involved in transmembrane signaling and activation of neutrophils.
The antibody was conjugated to BD Horizon™ BV650 which is part of the BD Horizon Brilliant™ Violet family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 650-nm. BD Horizon BV650 can be excited by the violet laser and detected in a filter used to detect APC-like dyes (eg, 660/20-nm filter). Due to the excitation and emission characteristics of the acceptor dye, there will be spillover into the APC and Alexa Fluor™ 700 detectors. However, the spillover can be corrected through compensation as with any other dye combination.
Specifications
CD66 | |
Monoclonal | |
0.2mg/mL | |
CEA, carcinoembryonic antigen, CD66a, CD66c, CD66d, CD66e | |
Mouse | |
Affinity Purified | |
RUO | |
Human | |
IgG2a κ |
Flow Cytometry | |
B1.1/CD66 | |
Brilliant Violet 650 | |
Aqueous buffered solution containing ≤0.09% sodium azide. | |
Human Breast Carcinoma Cells | |
50 μg | |
Primary | |
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
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For Research Use Only