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TCR γδ Mouse anti-Human, Brilliant Violet 510, Clone: B1, BD Optibuild™

Mouse Monoclonal Antibody

Manufacturer:  BD Biosciences 740179

Catalog No. BDB740179


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Description

Description

The B1 monoclonal antibody specifically binds to the γδ T cell receptor ( γδ TCR). This receptor complex consists of two disulfide-linked transmembrane glycoproteins, a γchain (45-60 kDa) and a δ subunit (40-60 kDa). The γδ TCR is associated with the signal-transducing CD3 complex. The γδ TCR is expressed by thymocytes and by peripheral T cell subsets (γδ T cells) that are located in the blood, liver, skin and various lymphoid and mucosal tissues. γδ T cells contribute to both innate and adaptive immune responses to infections and tumors. Reports suggest that γδ T cells may also play roles in antigen presentation and the regulation of autoimmune responses.

The antibody was conjugated to BD Horizon™ BV510 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 405-nm and Em Max at 510-nm, BD Horizon BV510 can be excited by the violet laser and detected in the BD Horizon V500 (525/50-nm) filter set. BD Horizon BV510 conjugates are useful for the detection of dim markers off the violet laser.

Specifications

Specifications

TCR γδ
B1
Brilliant Violet 510
Aqueous buffered solution containing ≤0.09% sodium azide.
Murine
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
RUO
Primary
Human
Flow Cytometry
0.2mg/mL
TCRgd; γδ TCR; TRG@, TRD@; TCRG, TCRD; TCR gamma delta
Affinity Purified
IgG1, κ
50μg
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Monoclonal
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