TCR γδ Mouse anti-Human, Brilliant Violet 786, Clone: B1, BD Optibuild™

Catalog No.	Quantity
BDB740995	50 μg

Catalog No. BDB740995 Supplier BD Biosciences Supplier No. 740995

Description

Mouse Monoclonal Antibody

The B1 monoclonal antibody specifically binds to the γδ T cell receptor ( γδ TCR). This receptor complex consists of two disulfide-linked transmembrane glycoproteins, a γchain (45-60 kDa) and a δ subunit (40-60 kDa). The γδ TCR is associated with the signal-transducing CD3 complex. The γδ TCR is expressed by thymocytes and by peripheral T cell subsets (γδ T cells) that are located in the blood, liver, skin and various lymphoid and mucosal tissues. γδ T cells contribute to both innate and adaptive immune responses to infections and tumors. Reports suggest that γδ T cells may also play roles in antigen presentation and the regulation of autoimmune responses.

The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405-nm and an acceptor dye with an Em Max at 786-nm. BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60-nm filter).

Specifications

• Antigen: TCR γδ
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: B1
• Concentration: 0.2mg/mL
• Conjugate: Brilliant Violet 786
• Description: TCRgd; γδ TCR; TRG@, TRD@; TCRG, TCRD; TCR gamma delta
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Host Species: Mouse
• Purification Method: Affinity Purified
• Quantity: 50 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
• Isotype: IgG1 κ

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

For Research Use Only