ICAM3, Mouse, PE, Clone: MEM-171, Abnova™

Catalog No.	Quantity
89-112-068	100 Reactions

Catalog No. 89-112-068 Supplier Abnova Corporation Supplier No. MAB5038

Description

Mouse monoclonal antibody raised against native ICAM3.

The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. [provided by RefSeq

Specifications

• Antigen: ICAM3
• Applications: Flow Cytometry
• Classification: Monoclonal
• Clone: MEM-171
• Conjugate: PE
• Description: Mouse monoclonal antibody raised against native ICAM3.
• Dilution: Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 10⁶ cells in a suspension) The optimal working dilution should be determined by the end user.
• Formulation: In PBS (0.2% BSA, 0.09% sodium azide)
• Gene: ICAM3
• Gene Alias: CD50/CDW50/ICAM-R
• Gene Symbols: ICAM3
• Host Species: Mouse
• Immunogen: Native purified ICAM3 from human granulocytes.
• Quantity: 100 Reactions
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 3385
• Test Specificity: This antibody MEM-171 recognizes an epitope in the D2 domain of CD50 (ICAM-3), a 120-130 KDa type I membrane protein (immunoglobulin supergene family) expressed on leukocytes, endothelial cells and Langerhans cells; it is negative on platelets and erythrocytes.
• Target Species: Human
• Content And Storage: Store in the dark at 4°C. Do not freeze.
  Avoid prolonged exposure to light.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1