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Description
Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence homology with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. A splice variant of this gene has been described. [provided by RefSeq
Specifications
Specifications
| Antigen | IDS |
| Applications | ELISA, Western Blot |
| Classification | Monoclonal |
| Clone | 3B4 |
| Conjugate | Unconjugated |
| Description | Mouse monoclonal antibody raised against a full-length recombinant IDS. |
| Formulation | ascites with no preservative |
| Gene | IDS |
| Gene Accession No. | BC006170 |
| Gene Alias | MPS2/SIDS |
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